Kim JD, Yoon NA, Jin S, Diano S (2019) Microglial UCP2 mediates inflammation and obesity induced by high fat feeding. Cell Metabolism 30:952-962. E5. doi: 10.1016/j.cmet2019.08.010. PMID: 31495690
Bruschetta G, Kim JD, Diano S*, Chan L (2018) Overexpression of Melanocortin 2 Receptor Accessory Protein 2 (MRAP2) in adult paraventricular MC4R neurons regulates energy intake and expenditure. Mol Met 18:79-87.doi:10.1016/j.molmet.2018.09.010. PMID:30352741 *co-corresponding author.
Bruschetta G, Jin S, Kim JD, Diano S (2018) Prolyl carboxypeptidase in Agouti-related Peptide neurons modulates food intake and body weight. Mol Met 10:28-38. doi: 10.1016/j.molmet.2018.02.003. PMID: 29459251
Kim JD, Toda C, Ramirez CM, Fernandez-Hernando C, Diano S (2017) Hypothalamic ventromedial Lin28a enhances glucose metabolism in diet-induced obesity. Diabetes, 66 (8):2102-2111. doi: 10.2337/db16-1558. PMID:28550108
Santoro A, Campolo M, Liu C, Sesaki H, Meli R, Liu ZW, Kim JD, Diano S (2017) DRP1 suppresses leptin and glucose sensing of POMC neurons. Cell Metabolism, 25(3):647-660. doi: 10.1016/j.cmet.2017.01.003. PMID: 28190775
Toda C, Kim JD, Impellizzeri D, Cuzzocrea S, Liu ZW, Diano S (2016) UCP2 regulates mitochondrial fission and ventromedial nucleus control of glucose responsiveness. Cell 164(5):872-83. doi: 10.1016/j.cell.2016.02.010. PMID: 26919426
Koch M, Varela L, Kim JG, Kim JD, Hernandez F, Simonds SE, Castorena CM, Vianna CR, Elmquist JK, Morozov YM, Rakic P, Bechmann I, Cowley MA, Szigeti-Buck K, Dietrich MO, Gao X-B, Diano S, Horvath TL (2015) Hypothalamic POMC neurons promote cannabinoid-induced feeding. Nature 519(7541):45-50. doi: 10.1038/nature14260.
Long L, Toda C, Jeong JK, Horvath TL, Diano S (2014) PPARg-deficient POMC neurons preserve weight control on obesogenic diet. J Clin Invest 124(9):4017-27. doi: 10.1172/JCI76220. PMID: 25083994
D’Agostino G, Kim JD, Liu ZW, Jeong JK, Suyama S, Calignano A, Gao XB, Schwartz M, Diano S (2013) Prolyl endopeptidase-deficient mice have reduced synaptic spine density in the CA1 region of the hippocampus and impaired LTP and spatial learning and memory. Cerebral Cortex(8):2007-2014.
Diano S, Liu ZW, Jeong JK, Dietrich MO, Ruan HB, Kim E, Suyama S, Kelly K, Gyengesi E, Arbiser JL, Belsham DD, Sarruf DA, Schwartz MW, Bennett A, Shanabrough M, Mobbs CV, Yang X, Gao XB, Horvath TL (2011) Peroxisome proliferation-related hypothalamic control of ROS sets melanocortin tone and feeding in diet-induced obesity. Nature Medicine2011 17(9):1121-7.
Andrews ZB, Liu ZW, Wallingford N, Erion DM, Borok E, Friedman JM, Tschoep MH, Shanabrough M, Cline GM, Shulman GI, Coppola A, Gao XB, Horvath TL, Diano S (2008) UCP2 mediates ghrelin’s action on NPY/AgRP neurons. Nature454(7206):846-51.
Coppola A, Liu ZW, Andrews ZB, Paradis E, Roy MC, Friedman JM, Ricquier D, Richard D, Horvath TL, Gao XB, Diano S. (2007) A central thermogenic-like mechanism in feeding regulation: an interplay between arcuate nucleus T3 and UCP2. Cell Metabolism5:21-33.
Gao Q, Mezei G, Nie Y, Rao Y, Choi CS, Bechmann I, Leranth C, Toran-Allerand D, Priest CA, Roberts JL, Gao XB, Mobbs C, Shulman GI, Diano S, Horvath TL. (2007) Anorectic estrogen mimics leptin's effect on the rewiring of melanocortin cells and Stat3 signaling in obese animals. Nature Medicine. 13(1):89-94.
Diano S, Farr SA, Benoit SC, Mcnay EC, da Silva I, Horvath B, Gaskin FS, Nonaka N, Jaeger LB, Xu L, Banks WA, Morley JE, Pinto S, Sherwin RS, Yamada KA, Sleeman MW, Tschöp MH, Horvath TL. (2006) Ghrelin controls hippocampal spine synapse density and memory performance. Nature Neuroscience9(3):381-8.
Editorial, reviews, chapters, books
Yoon N, Diano S (2021) Hypothalamic glucose sensing mechanisms. Diabetologia DOI: 10.1007/s00125-021-05395-6 PMID: 33544170
Quarta C, Claret M, Zeltser LM, Williams KW, Yeo GSH, Tschoep MH, Diano S, Bruening JC, Cota D. (2021) POMC neuronal heterogeneity in energy balance and beyond: an integrated view. Nat Metab. 2021 Feb 25. doi: 10.1038/s42255-021-00345-3.
Kim JD, Diano S (2020) A sympathetic treatment for obesity. Cell Metabolism 31(6):1043-1045. doi: 10.1016/j.cmet.2020.05.009.PMID: 32492388
Bruschetta G, Diano S (2019) Brain-to-pancreas signaling axis links nicotine and diabetes. Nature574;336-337. Doi: 10.1038/d41586-019-02975-w. PMID: 31619783
Jin S, Diano S (2018) Mitochondrial dynamics and hypothalamic regulation of metabolism. Endocrinology. 2018 Oct 1;159(10):3596-3604. doi: 10.1210/en.2018-00667.
Diano S (2018) A new brain circuit in feeding control. Science 361:29-30. doi:10.1126/science.aau1419.
Toda C, Santoro A, Kim JD, Diano S (2017) POMC neurons: from birth to death. Annual Review of Physiology 79:209-236. 79:209-236. doi: 10.1146/annurev-physiol-022516-034110.PMID: 28192062